Bristol to Seattle: a journey of scientific curiosity and christian faith
Friday, 24 April 2026
P is for Passage
Thursday, 23 April 2026
O is for outing
Conference day 4:
A few pictures from by my hotel.

Today I missed a session of the conference to go in a little later, taking the opportunity to go on a CityCat. These ferry's run every 15 mins or so and cost only 50 cents, for that you can go ~45 mins down river.
We went about 20-30 mins down river and then turned back to get tot the conference for 11am. You can see all the green trees and plants amongst and on the buildings.
At lunch time we went for a little walk to grab an ice cream and found this guys waiting around to steal food left unattended.

Lots of interesting science between the outings too. Updates on some clinical trials to prevent type 1 diabetes or improve glucose tolerance for those who are already diagnosed. Work on pancreata donated by organ donors, showing how the pancreas develops in people with type 1. Lab techniques make it possible to identify the different cells, count them, even find out what proteins they are making. Possibly the best part was pancreas slices (sections of recently donated pancreas) that are kept alive to allow scientists to understand how the immune cells damage the pancreas. They even had videos of immune cells destroying the insulin making cells in these sections over 16 hours. Really cutting edge work that is only made possible by the gracious gift of these organs by donors and their families.
Wednesday, 22 April 2026
N is for Nine
Conference day 3. This morning I woke up from a dream where I was drowning at about 5:30 am. Was a bit hard to fall back to sleep after that. I spent the morning getting up and finishing my second talk for the day, mainly by prettifying it with pointless images (no graphs in this talk). It turns out both of my talks are about nine minutes, I was aiming for eight, but close enough!
Unfortunately by the time I'd done that and run through what I needed to say I missed the first session so I headed over to the conference venue for the second session starting at 9:10 and my first speaking engagement of the day.
This did afford the opportunity to get a better photo of the Brisbane sign.
Talk number 1:
This is the talk that contributes to the cost of my conference travel. As part of the Islet Autoantibody Standardization Program committee. We had 50 mins scheduled, started 5 mins early and over ran by only 10 mins, which for us is pretty good! Antibodies are proteins which recognise different patterns, this way they can recognise specific proteins or sugars. They can then take in dangerous proteins or sugars (i.e. ones from bacteria or viruses) and show them to T-cells, to make the T-cells switch on their killing activity. In type 1 diabetes they get confused and think the proteins from the insulin producing cells are dangerous.
M is for Marvelous
Conference day two. Today is the day I have to upload my talks to the conference portal. I was planning to do some work on them before the conference started but somehow by the time I got up, had a shower, and ironed my shirts, it was time to head out for breakfast and the Plenary Lecture starting at 8:30am.
Today was 'T-cell' day, it's a bit of a shame the microbiota didn't land on the 'M' day, but that's life. Put simply T-cells are the cells of the immune system that do the killing in type 1 diabetes, all the other cells of the immune system 'just' help them do it.
I spent most of today trying to finish my talks whilst listening in for anything particularly interesting. Such as, the harmonisation of pancreas specific immune cell assays between laboratories (measuring the cells that home to the insulin producing cells specifically).
By the end of the day I had succeeded in uploading one talk to the conference portal, with one more to go.
That did mean I could enjoy the Rising Star Award Session, all early career researchers presenting their work, with an award of travel money, certificate, and a conference dinner ticket! These were nice, novel, well explained presentations.
This evening I only had to stay at the conference centre to talk with my committee till 7:15pm. Then we found my other colleagues for some food.
Back to the hotel room and practice my finished talk for tomorrow...
L is for Lick...
The slow posting is because on Monday (letter L day) my conference started. L could also stand for long day, though not as long as the rest of the week. Today we started at 10am with registration and 11am for the Welcome.
Today was mainly about the early life origins of type 1 diabetes, mainly microbiota. The most memorable talk, the sharing of gut bacterial strains between infants and their families. Obviously, babies start of with strong sharing of strains with their Mum's, persisting as long as they are breast fed. However then their strains start to shift towards their older siblings, it's not clear why, possibly because their guts have a more similar bacterial niche (environment), such as a more similar diet. Then children start nursery and their bacterial strains shift again to shared strains with their peers. Ick!
We finished the conference about 5:30pm but I was at the conference venue until 9pm working with my committee on our presentations for Wednesday.
We left to find food but all the restaurants kitchens were closing so eventually we ended up in the central shopping area having Mc Donald's at 10pm. Raspberry Fanta - yum!




















